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Extant fold-switching proteins are widespread
A central tenet of biology is that globular proteins have a unique 3D structure under physiological conditions. Recent work has challenged this notion by demonstrating that some proteins switch folds, a process that involves remodeling of secondary structure in response to a few mutations (evolved f...
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| I publikationen: | Proc Natl Acad Sci U S A |
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| Huvudupphovsmän: | , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
National Academy of Sciences
2018
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6003340/ https://ncbi.nlm.nih.gov/pubmed/29784778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1800168115 |
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