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Continuous intrathecal orexin delivery inhibits cataplexy in a murine model of narcolepsy
Narcolepsy–cataplexy is a chronic neurological disorder caused by loss of orexin (hypocretin)-producing neurons, associated with excessive daytime sleepiness, sleep attacks, cataplexy, sleep paralysis, hypnagogic hallucinations, and fragmentation of nighttime sleep. Currently, human narcolepsy is tr...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6003319/ https://ncbi.nlm.nih.gov/pubmed/29784823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1722686115 |
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