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Two subunits of the exocyst, Sec3p and Exo70p, can function exclusively on the plasma membrane

The exocyst is an octameric complex that tethers secretory vesicles to the plasma membrane in preparation for fusion. We anchored each subunit with a transmembrane (TM) domain at its N- or C-terminus. Only N-terminally anchored TM-Sec3p and C-terminally anchored Exo70p-TM proved functional. These fi...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Liu, Dongmei, Li, Xia, Shen, David, Novick, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003224/
https://ncbi.nlm.nih.gov/pubmed/29343551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-08-0518
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