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Two subunits of the exocyst, Sec3p and Exo70p, can function exclusively on the plasma membrane

The exocyst is an octameric complex that tethers secretory vesicles to the plasma membrane in preparation for fusion. We anchored each subunit with a transmembrane (TM) domain at its N- or C-terminus. Only N-terminally anchored TM-Sec3p and C-terminally anchored Exo70p-TM proved functional. These fi...

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Bibliografische gegevens
Gepubliceerd in:Mol Biol Cell
Hoofdauteurs: Liu, Dongmei, Li, Xia, Shen, David, Novick, Peter
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Cell Biology 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003224/
https://ncbi.nlm.nih.gov/pubmed/29343551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-08-0518
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