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Genetic Reduction or Negative Modulation of mGlu(7) Does Not Impact Anxiety and Fear Learning Phenotypes in a Mouse Model of MECP2 Duplication Syndrome

Rett syndrome and MECP2 Duplication syndrome are neurodevelopmental disorders attributed to loss-of-function mutations in, or duplication of, the gene encoding methyl-CpG-binding protein 2 (MeCP2), respectively. We recently reported decreased expression and function of the metabotropic glutamate rec...

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Detalhes bibliográficos
Publicado no:ACS Chem Neurosci
Main Authors: Fisher, Nicole M., Gogliotti, Rocco G., Vermudez, Sheryl Anne D., Stansley, Branden J., Conn, P. Jeffrey, Niswender, Colleen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002927/
https://ncbi.nlm.nih.gov/pubmed/29227625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.7b00414
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