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α(2)-Macroglobulin Is a Significant In Vivo Inhibitor of Activated Protein C and Low APC:α(2)M Levels Are Associated with Venous Thromboembolism
BACKGROUND: Activated protein C (APC) is a major regulator of thrombin formation. Two major plasma inhibitors form complexes with APC, protein Cinhibitor (PCI) andα(1)-antitrypsin (α(1)AT), and these complexes have been quantified by specific enzyme-linked immunosorbent assays (ELISAs). Also, comple...
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| Publicado no: | Thromb Haemost |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6002867/ https://ncbi.nlm.nih.gov/pubmed/29448296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0038-1629902 |
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