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Monocyte Subsets Have Distinct Patterns of Tetraspanin Expression and Different Capacities to Form Multinucleate Giant Cells

Monocytes are able to undergo homotypic fusion to produce different types of multinucleated giant cells, such as Langhans giant cells in response to M. tuberculosis infection or foreign body giant cells in response to implanted biomaterials. Monocyte fusion is highly coordinated and complex, with va...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Champion, Thomas C., Partridge, Lynda J., Ong, Siew-Min, Malleret, Benoit, Wong, Siew-Cheng, Monk, Peter N.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002745/
https://ncbi.nlm.nih.gov/pubmed/29937768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01247
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