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Monocyte progenitors give rise to multinucleated giant cells
The immune response to mycobacteria is characterized by granuloma formation, which features multinucleated giant cells as a unique macrophage type. We previously found that multinucleated giant cells result from Toll-like receptor-induced DNA damage and cell autonomous cell cycle modifications. Howe...
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| 發表在: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8016882/ https://ncbi.nlm.nih.gov/pubmed/33795674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22103-5 |
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