Monocyte progenitors give rise to multinucleated giant cells

The immune response to mycobacteria is characterized by granuloma formation, which features multinucleated giant cells as a unique macrophage type. We previously found that multinucleated giant cells result from Toll-like receptor-induced DNA damage and cell autonomous cell cycle modifications. Howe...

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Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Lösslein, Anne Kathrin, Lohrmann, Florens, Scheuermann, Lisa, Gharun, Kourosh, Neuber, Jana, Kolter, Julia, Forde, Aaron James, Kleimeyer, Christian, Poh, Ying Yee, Mack, Matthias, Triantafyllopoulou, Antigoni, Dunlap, Micah D., Khader, Shabaana A., Seidl, Maximilian, Hölscher, Alexandra, Hölscher, Christoph, Guan, Xue Li, Dorhoi, Anca, Henneke, Philipp
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2021
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016882/
https://ncbi.nlm.nih.gov/pubmed/33795674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22103-5
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