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Inefficient HIV-1 trans Infection of CD4(+) T Cells by Macrophages from HIV-1 Nonprogressors Is Associated with Altered Membrane Cholesterol and DC-SIGN

Professional antigen-presenting cells (APC; myeloid dendritic cells [DC] and macrophages [MΦ]; B lymphocytes) mediate highly efficient HIV-1 infection of CD4(+) T cells, termed trans infection, that could contribute to HIV-1 pathogenesis. We have previously shown that lower cholesterol content in DC...

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Bibliografische gegevens
Gepubliceerd in:J Virol
Hoofdauteurs: DeLucia, Diana C., Rinaldo, Charles R., Rappocciolo, Giovanna
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002718/
https://ncbi.nlm.nih.gov/pubmed/29643243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00092-18
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