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A GXXXA Motif in the Transmembrane Domain of the Ebola Virus Glycoprotein Is Required for Tetherin Antagonism

The interferon-induced antiviral host cell protein tetherin can inhibit the release of several enveloped viruses from infected cells. The Ebola virus (EBOV) glycoprotein (GP) antagonizes tetherin, but the domains and amino acids in GP that are required for tetherin antagonism have not been fully def...

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Vydáno v:J Virol
Hlavní autoři: González-Hernández, Mariana, Hoffmann, Markus, Brinkmann, Constantin, Nehls, Julia, Winkler, Michael, Schindler, Michael, Pöhlmann, Stefan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002716/
https://ncbi.nlm.nih.gov/pubmed/29669839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00403-18
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