Recombinant Porcine Reproductive and Respiratory Syndrome Virus Expressing Membrane-Bound Interleukin-15 as an Immunomodulatory Adjuvant Enhances NK and γδ T Cell Responses and Confers Heterologous Protection

Cytokines are often used as adjuvants to improve vaccine immunogenicity, since they are important in initiating and shaping the immune response. The available commercial modified live-attenuated vaccines (MLVs) against porcine reproductive and respiratory syndrome virus (PRRSV) are unable to mount s...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Cao, Qian M., Ni, Yan-Yan, Cao, Dianjun, Tian, Debin, Yugo, Danielle M., Heffron, C. Lynn, Overend, Christopher, Subramaniam, Sakthivel, Rogers, Adam J., Catanzaro, Nicholas, LeRoith, Tanya, Roberts, Paul C., Meng, Xiang-Jin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2018
Aiheet:
Vaccines and Antiviral Agents
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002708/
https://ncbi.nlm.nih.gov/pubmed/29643245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00007-18
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