E1B-55K-Mediated Regulation of RNF4 SUMO-Targeted Ubiquitin Ligase Promotes Human Adenovirus Gene Expression

Human adenovirus (HAdV) E1B-55K is a multifunctional regulator of productive viral replication and oncogenic transformation in nonpermissive mammalian cells. These functions depend on E1B-55K's posttranslational modification with the SUMO protein and its binding to HAdV E4orf6. Both early viral...

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Publicado en:J Virol
Autores principales: Müncheberg, Sarah, Hay, Ron T., Ip, Wing H., Meyer, Tina, Weiß, Christina, Brenke, Jara, Masser, Sawinee, Hadian, Kamyar, Dobner, Thomas, Schreiner, Sabrina
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2018
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002701/
https://ncbi.nlm.nih.gov/pubmed/29695423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00164-18
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