IreA Controls Endoplasmic Reticulum Stress-Induced Autophagy and Survival through Homeostasis Recovery

The unfolded protein response (UPR) is an adaptive pathway that restores cellular homeostasis after endoplasmic reticulum (ER) stress. The ER-resident kinase/RNase Ire1 is the only UPR sensor conserved during evolution. Autophagy, a lysosomal degradative pathway, also contributes to the recovery of...

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Udgivet i:Mol Cell Biol
Main Authors: Domínguez-Martín, Eunice, Ongay-Larios, Laura, Kawasaki, Laura, Vincent, Olivier, Coello, Gerardo, Coria, Roberto, Escalante, Ricardo
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002696/
https://ncbi.nlm.nih.gov/pubmed/29632077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00054-18
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