Multi-Donor Longitudinal Antibody Repertoire Sequencing Reveals the Existence of Public Antibody Clonotypes in HIV-1 Infection

Characterization of single antibody lineages within infected individuals has provided insights into the development of Env-specific antibodies. However, a systems-level understanding of the humoral response against HIV-1 is limited. Here, we interrogated the antibody repertoires of multiple HIV-infe...

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Veröffentlicht in:Cell Host Microbe
Hauptverfasser: Setliff, Ian, McDonnell, Wyatt J., Raju, Nagarajan, Bombardi, Robin G., Murji, Amyn A., Scheepers, Cathrine, Ziki, Rutendo, Mynhardt, Charissa, Shepherd, Bryan E., Mamchak, Alusha A., Garrett, Nigel, Karim, Salim Abdool, Mallal, Simon A., Crowe, James E., Morris, Lynn, Georgiev, Ivelin S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cell Press 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002606/
https://ncbi.nlm.nih.gov/pubmed/29861170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2018.05.001
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