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Quantitative in vivo whole genome motility screen reveals novel therapeutic targets to block cancer metastasis
Metastasis is the most lethal aspect of cancer, yet current therapeutic strategies do not target its key rate-limiting steps. We have previously shown that the entry of cancer cells into the blood stream, or intravasation, is highly dependent upon in vivo cancer cell motility, making it an attractiv...
Enregistré dans:
| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6002534/ https://ncbi.nlm.nih.gov/pubmed/29904055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04743-2 |
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