Lipid A Has Significance for Optimal Growth of Coxiella burnetii in Macrophage-Like THP-1 Cells and to a Lesser Extent in Axenic Media and Non-phagocytic Cells

Lipid A is an essential basal component of lipopolysaccharide of most Gram-negative bacteria. Inhibitors targeting LpxC, a conserved enzyme in lipid A biosynthesis, are antibiotic candidates against Gram-negative pathogens. Here we report the characterization of the role of lipid A in Coxiella burne...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Wang, Tao, Yu, Yonghui, Liang, Xiaofei, Luo, Shengdong, He, Zemin, Sun, Zhihui, Jiang, Yongqiang, Omsland, Anders, Zhou, Pei, Song, Lihua
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002510/
https://ncbi.nlm.nih.gov/pubmed/29938202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2018.00192
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