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Pharmacological activation of epidermal growth factor receptor signaling inhibits colitis-associated cancer in mice
Current treatments for inflammatory bowel disease (IBD) target the overactive immune response of the intestinal mucosa. However, epidermal growth factor (EGF), an activating ligand of the EGF receptor (EGFR), has been shown to induce disease remission through direct targeting of intestinal mucosal h...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6002410/ https://ncbi.nlm.nih.gov/pubmed/29904166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27353-w |
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