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Pharmacological activation of epidermal growth factor receptor signaling inhibits colitis-associated cancer in mice

Current treatments for inflammatory bowel disease (IBD) target the overactive immune response of the intestinal mucosa. However, epidermal growth factor (EGF), an activating ligand of the EGF receptor (EGFR), has been shown to induce disease remission through direct targeting of intestinal mucosal h...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Dubé, Philip E., Liu, Cambrian Y., Girish, Nandini, Washington, M. Kay, Polk, D. Brent
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002410/
https://ncbi.nlm.nih.gov/pubmed/29904166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27353-w
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