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Serine/Threonine Kinase CHEK1-Dependent Transcriptional Regulation of RAD54L Promotes Proliferation and Radio Resistance in Glioblastoma

Accumulating evidence indicates that Checkpoint kinase 1 (CHEK1) plays an essential role in tumor cells and that it could induce cell proliferation and could be related to prognosis in multiple types of cancer. However, the biological role and molecular mechanism of CHEK1 in GBM still remain unclear...

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Detalhes bibliográficos
Publicado no:Transl Oncol
Main Authors: Bai, Xiaobin, Wang, Jia, Huo, Longwei, Xie, Yuchen, Xie, Wanfu, Xu, Gaofeng, Wang, Maode
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002345/
https://ncbi.nlm.nih.gov/pubmed/29287241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2017.11.007
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