Serine/Threonine Kinase CHEK1-Dependent Transcriptional Regulation of RAD54L Promotes Proliferation and Radio Resistance in Glioblastoma

Accumulating evidence indicates that Checkpoint kinase 1 (CHEK1) plays an essential role in tumor cells and that it could induce cell proliferation and could be related to prognosis in multiple types of cancer. However, the biological role and molecular mechanism of CHEK1 in GBM still remain unclear...

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Bibliografiske detaljer
Udgivet i:Transl Oncol
Main Authors: Bai, Xiaobin, Wang, Jia, Huo, Longwei, Xie, Yuchen, Xie, Wanfu, Xu, Gaofeng, Wang, Maode
Format: Artigo
Sprog:Inglês
Udgivet: Neoplasia Press 2017
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Original article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002345/
https://ncbi.nlm.nih.gov/pubmed/29287241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2017.11.007
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