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Galectin‐3 is an amplifier of the interleukin‐1β‐mediated inflammatory response in corneal keratinocytes

Interleukin‐1β (IL‐1β) is a potent mediator of innate immunity commonly up‐regulated in a broad spectrum of inflammatory diseases. When bound to its cell surface receptor, IL‐1β initiates a signalling cascade that cooperatively induces the expression of canonical IL‐1 target genes such as IL‐8 and I...

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Vydáno v:Immunology
Hlavní autoři: Uchino, Yuichi, Woodward, Ashley M., Mauris, Jérôme, Peterson, Kristoffer, Verma, Priya, Nilsson, Ulf J., Rajaiya, Jaya, Argüeso, Pablo
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002218/
https://ncbi.nlm.nih.gov/pubmed/29359328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12899
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