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Binding of Transmembrane Mucins to Galectin-3 Limits Herpesvirus 1 Infection of Human Corneal Keratinocytes

Epithelial cells lining mucosal surfaces impose multiple barriers to viral infection. At the ocular surface, the carbohydrate-binding protein galectin-3 maintains barrier function by cross-linking transmembrane mucins on the apical glycocalyx. Despite these defense mechanisms, many viruses have evol...

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Autors principals: Woodward, A. M., Mauris, J., Argüeso, P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648170/
https://ncbi.nlm.nih.gov/pubmed/23487460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00166-13
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