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β1 subunit stabilises sodium channel Nav1.7 against mechanical stress

KEY POINTS: The voltage‐gated sodium channel Nav1.7 is a key player in neuronal excitability and pain signalling. In addition to voltage sensing, the channel is also modulated by mechanical stress. Using whole‐cell patch‐clamp experiments, we discovered that the sodium channel subunit β1 is able to...

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Bibliografische gegevens
Gepubliceerd in:J Physiol
Hoofdauteurs: Körner, Jannis, Meents, Jannis, Machtens, Jan‐Philipp, Lampert, Angelika
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002208/
https://ncbi.nlm.nih.gov/pubmed/29659026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP275905
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