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Defects in intracellular trafficking of fungal cell wall synthases lead to aberrant host immune recognition

The human fungal pathogen, Cryptococcus neoformans, dramatically alters its cell wall, both in size and composition, upon entering the host. This cell wall remodeling is essential for host immune avoidance by this pathogen. In a genetic screen for mutants with changes in their cell wall, we identifi...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Esher, Shannon K., Ost, Kyla S., Kohlbrenner, Maria A., Pianalto, Kaila M., Telzrow, Calla L., Campuzano, Althea, Nichols, Connie B., Munro, Carol, Wormley, Floyd L., Alspaugh, J. Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002136/
https://ncbi.nlm.nih.gov/pubmed/29864141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007126
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