Defects in intracellular trafficking of fungal cell wall synthases lead to aberrant host immune recognition

The human fungal pathogen, Cryptococcus neoformans, dramatically alters its cell wall, both in size and composition, upon entering the host. This cell wall remodeling is essential for host immune avoidance by this pathogen. In a genetic screen for mutants with changes in their cell wall, we identifi...

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Udgivet i:PLoS Pathog
Main Authors: Esher, Shannon K., Ost, Kyla S., Kohlbrenner, Maria A., Pianalto, Kaila M., Telzrow, Calla L., Campuzano, Althea, Nichols, Connie B., Munro, Carol, Wormley, Floyd L., Alspaugh, J. Andrew
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002136/
https://ncbi.nlm.nih.gov/pubmed/29864141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007126
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