Phosphate-dependent FGF23 secretion is modulated by PiT2/Slc20a2

OBJECTIVE: The canonical role of the bone-derived fibroblast growth factor 23 (Fgf23) is to regulate the serum inorganic phosphate (Pi) level. As part of a feedback loop, serum Pi levels control Fgf23 secretion through undefined mechanisms. We recently showed in vitro that the two high-affinity Na(+...

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Dettagli Bibliografici
Pubblicato in:Mol Metab
Autori principali: Bon, Nina, Frangi, Giulia, Sourice, Sophie, Guicheux, Jérôme, Beck-Cormier, Sarah, Beck, Laurent
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2018
Soggetti:
Brief Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001877/
https://ncbi.nlm.nih.gov/pubmed/29551636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.02.007
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