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Sirtuin-4 (SIRT4), a therapeutic target with oncogenic and tumor-suppressive activity in cancer

Several members of the sirtuin (SIRT) family, a highly conserved family of NAD(+)-dependent enzymes, have been shown to play a critical role in both promoting and/or suppressing tumorigenesis. In this study, recent progress in the field concerning SIRT4 and cancer was reviewed, and the relationship...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Huang, Guoyu, Zhu, Guanbao
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001835/
https://ncbi.nlm.nih.gov/pubmed/29928130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S157724
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