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Sirtuin-3 (SIRT3), a therapeutic target with oncogenic and tumor-suppressive function in cancer
Sirtuin-3 (SIRT3), a major mitochondria NAD+-dependent deacetylase, may target mitochondrial proteins for lysine deacetylation and also regulate cellular functions. And, SIRT3 is an emerging instrumental regulator of the mitochondrial adaptive response to stress, such as metabolic reprogramming and...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3944233/ https://ncbi.nlm.nih.gov/pubmed/24503539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.14 |
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