Campath, calcineurin inhibitor reduction, and chronic allograft nephropathy (the 3C Study) – results of a randomized controlled clinical trial

Calcineurin inhibitors (CNIs, eg, tacrolimus) reduce short‐term kidney transplant failure, but chronic nephrotoxicity may contribute to late transplant loss. Elective conversion to inhibitors of the mammalian target of rapamycin (mTOR, eg, sirolimus) pathway might avoid long‐term CNI renal damage an...

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Vydáno v:Am J Transplant
Hlavní autoři: Haynes, Richard, Blackwell, Lisa, Staplin, Natalie, Herrington, William G., Emberson, Jonathan, Judge, Parminder K., Storey, Benjamin C., Landray, Martin J., Harden, Paul N., Baigent, Colin, Friend, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
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ORIGINAL ARTICLES
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001618/
https://ncbi.nlm.nih.gov/pubmed/29226570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.14619
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