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Campath, calcineurin inhibitor reduction, and chronic allograft nephropathy (the 3C Study) – results of a randomized controlled clinical trial

Calcineurin inhibitors (CNIs, eg, tacrolimus) reduce short‐term kidney transplant failure, but chronic nephrotoxicity may contribute to late transplant loss. Elective conversion to inhibitors of the mammalian target of rapamycin (mTOR, eg, sirolimus) pathway might avoid long‐term CNI renal damage an...

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Detalles Bibliográficos
Publicado en:Am J Transplant
Main Authors: Haynes, Richard, Blackwell, Lisa, Staplin, Natalie, Herrington, William G., Emberson, Jonathan, Judge, Parminder K., Storey, Benjamin C., Landray, Martin J., Harden, Paul N., Baigent, Colin, Friend, Peter
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001618/
https://ncbi.nlm.nih.gov/pubmed/29226570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.14619
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