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Campath, calcineurin inhibitor reduction, and chronic allograft nephropathy (the 3C Study) – results of a randomized controlled clinical trial

Calcineurin inhibitors (CNIs, eg, tacrolimus) reduce short‐term kidney transplant failure, but chronic nephrotoxicity may contribute to late transplant loss. Elective conversion to inhibitors of the mammalian target of rapamycin (mTOR, eg, sirolimus) pathway might avoid long‐term CNI renal damage an...

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Detalhes bibliográficos
Publicado no:Am J Transplant
Main Authors: Haynes, Richard, Blackwell, Lisa, Staplin, Natalie, Herrington, William G., Emberson, Jonathan, Judge, Parminder K., Storey, Benjamin C., Landray, Martin J., Harden, Paul N., Baigent, Colin, Friend, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001618/
https://ncbi.nlm.nih.gov/pubmed/29226570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.14619
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