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Hyperpolarized ketone body metabolism in the rat heart

The aim of this work was to investigate the use of (13)C‐labelled acetoacetate and β‐hydroxybutyrate as novel hyperpolarized substrates in the study of cardiac metabolism. [1‐(13)C]Acetoacetate was synthesized by catalysed hydrolysis, and both it and [1‐(13)C]β‐hydroxybutyrate were hyperpolarized by...

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Publicat a:NMR Biomed
Autors principals: Miller, Jack J., Ball, Daniel R., Lau, Angus Z., Tyler, Damian J.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001529/
https://ncbi.nlm.nih.gov/pubmed/29637642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.3912
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