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Hyperpolarized ketone body metabolism in the rat heart

The aim of this work was to investigate the use of (13)C‐labelled acetoacetate and β‐hydroxybutyrate as novel hyperpolarized substrates in the study of cardiac metabolism. [1‐(13)C]Acetoacetate was synthesized by catalysed hydrolysis, and both it and [1‐(13)C]β‐hydroxybutyrate were hyperpolarized by...

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Detalhes bibliográficos
Publicado no:NMR Biomed
Main Authors: Miller, Jack J., Ball, Daniel R., Lau, Angus Z., Tyler, Damian J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001529/
https://ncbi.nlm.nih.gov/pubmed/29637642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.3912
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