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Nucleophilic Substitution (S(N)2): Dependence on Nucleophile, Leaving Group, Central Atom, Substituents, and Solvent

The reaction potential energy surface (PES), and thus the mechanism of bimolecular nucleophilic substitution (S(N)2), depends profoundly on the nature of the nucleophile and leaving group, but also on the central, electrophilic atom, its substituents, as well as on the medium in which the reaction t...

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Detalhes bibliográficos
Publicado no:Chemphyschem
Main Authors: Hamlin, Trevor A., Swart, Marcel, Bickelhaupt, F. Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001448/
https://ncbi.nlm.nih.gov/pubmed/29542853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cphc.201701363
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