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Mir‐29b promotes human aortic valve interstitial cell calcification via inhibiting TGF‐β3 through activation of wnt3/β‐catenin/Smad3 signaling

Herein, we hypothesized that pro‐osteogenic MicroRNAs (miRs) could play functional roles in the calcification of the aortic valve and aimed to explore the functional role of miR‐29b in the osteoblastic differentiation of human aortic valve interstitial cells (hAVICs) and the underlying molecular mec...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Biochem
Hauptverfasser: Fang, Ming, Wang, Cheng‐Guang, Zheng, Changzhu, Luo, Jun, Hou, Shiqiang, Liu, Kangyong, Li, Xinming
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001435/
https://ncbi.nlm.nih.gov/pubmed/29227539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.26545
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