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Mir‐29b promotes human aortic valve interstitial cell calcification via inhibiting TGF‐β3 through activation of wnt3/β‐catenin/Smad3 signaling

Herein, we hypothesized that pro‐osteogenic MicroRNAs (miRs) could play functional roles in the calcification of the aortic valve and aimed to explore the functional role of miR‐29b in the osteoblastic differentiation of human aortic valve interstitial cells (hAVICs) and the underlying molecular mec...

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Detalles Bibliográficos
Publicado en:J Cell Biochem
Main Authors: Fang, Ming, Wang, Cheng‐Guang, Zheng, Changzhu, Luo, Jun, Hou, Shiqiang, Liu, Kangyong, Li, Xinming
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001435/
https://ncbi.nlm.nih.gov/pubmed/29227539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.26545
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