The suppression of DUSP5 expression correlates with paclitaxel resistance and poor prognosis in basal-like breast cancer

Basal-like breast cancer (BLBC) is resistant to endocrinotherapy and targeted therapy and new molecular therapies are needed for BLBC. In this study, we evaluated the role of DUSP1 and DUSP5, negative regulators of mitogen-activated protein kinase pathway, in the aggressiveness of BLBC. MDA-MB-231 c...

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Enregistré dans:
Détails bibliographiques
Publié dans:Int J Med Sci
Auteurs principaux: Liu, Tieju, Sun, Huizhi, Liu, Shiqi, Yang, Zhao, Li, Linqi, Yao, Nan, Cheng, Siqi, Dong, Xueyi, Liang, Xiaohui, Chen, Chen, Wang, Yi, Zhao, Xiulan
Format: Artigo
Langue:Inglês
Publié: Ivyspring International Publisher 2018
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001410/
https://ncbi.nlm.nih.gov/pubmed/29910679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.24981
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