The suppression of DUSP5 expression correlates with paclitaxel resistance and poor prognosis in basal-like breast cancer

Basal-like breast cancer (BLBC) is resistant to endocrinotherapy and targeted therapy and new molecular therapies are needed for BLBC. In this study, we evaluated the role of DUSP1 and DUSP5, negative regulators of mitogen-activated protein kinase pathway, in the aggressiveness of BLBC. MDA-MB-231 c...

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Bibliografiske detaljer
Udgivet i:Int J Med Sci
Main Authors: Liu, Tieju, Sun, Huizhi, Liu, Shiqi, Yang, Zhao, Li, Linqi, Yao, Nan, Cheng, Siqi, Dong, Xueyi, Liang, Xiaohui, Chen, Chen, Wang, Yi, Zhao, Xiulan
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2018
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001410/
https://ncbi.nlm.nih.gov/pubmed/29910679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.24981
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