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GSK-3 promotes S-phase entry and progression in C. elegans germline stem cells to maintain tissue output

Adult C. elegans germline stem cells (GSCs) and mouse embryonic stem cells (mESCs) exhibit a non-canonical cell cycle structure with an abbreviated G1 phase and phase-independent expression of Cdk2 and cyclin E. Mechanisms that promote the abbreviated cell cycle remain unknown, as do the consequence...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Furuta, Tokiko, Joo, Hyoe-Jin, Trimmer, Kenneth A., Chen, Shin-Yu, Arur, Swathi
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001380/
https://ncbi.nlm.nih.gov/pubmed/29695611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.161042
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