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The Role of Structural Enthalpy in Spherical Nucleic Acid Hybridization
DNA hybridization onto DNA-functionalized nanoparticle surfaces (e.g., in the form of a spherical nucleic acid (SNA)) is known to be enhanced relative to hybridization free in solution. Surprisingly, via isothermal titration calorimetry, we reveal that this enhancement is enthalpically, as opposed t...
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6001361/ https://ncbi.nlm.nih.gov/pubmed/29762017 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b03459 |
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