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Copper mediated C–H amination with oximes: en route to primary anilines

Here we report an efficient Cu(i)-mediated C–H amination reaction with oximes as amino donors to introduce NH(2) groups directly. Various strongly coordinating heterocycles including quinoline, pyrimidine, pyrazine, pyrazole and triazole were tolerated well. The potential utility was further demonst...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Chem Sci
Hauptverfasser: Xu, Lin-Lin, Wang, Xing, Ma, Biao, Yin, Ming-Xing, Lin, Hai-Xia, Dai, Hui-Xiong, Yu, Jin-Quan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Royal Society of Chemistry 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001278/
https://ncbi.nlm.nih.gov/pubmed/29997868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc01256c
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