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Safety of 4-factor prothrombin complex concentrate (4F-PCC) for emergent reversal of factor Xa inhibitors

BACKGROUND: Although factor Xa inhibitors have become a popular choice for chronic oral anticoagulation, effective drug reversal remains difficult due to a lack of specific antidote. Currently, 4-factor prothrombin complex concentrate (4F-PCC) is considered the treatment of choice for factor Xa inhi...

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Vydáno v:J Intensive Care
Hlavní autoři: Tao, Jing, Bukanova, Elena N., Akhtar, Shamsuddin
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001072/
https://ncbi.nlm.nih.gov/pubmed/29942519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40560-018-0303-y
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