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Sleeping Beauty and the Microenvironment Enchantment: Microenvironmental Regulation of the Proliferation-Quiescence Decision in Normal Tissues and in Cancer Development

Cells from prokaryota to the more complex metazoans cease proliferating at some point in their lives and enter a reversible, proliferative-dormant state termed quiescence. The appearance of quiescence in the course of evolution was essential to the acquisition of multicellular specialization and com...

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Pubblicato in:Front Cell Dev Biol
Autori principali: Fiore, Ana Paula Zen Petisco, Ribeiro, Pedro de Freitas, Bruni-Cardoso, Alexandre
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001001/
https://ncbi.nlm.nih.gov/pubmed/29930939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2018.00059
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