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Stratification of candidate genes for Parkinson’s disease using weighted protein-protein interaction network analysis

BACKGROUND: Genome wide association studies (GWAS) have helped identify large numbers of genetic loci that significantly associate with increased risk of developing diseases. However, translating genetic knowledge into understanding of the molecular mechanisms underpinning disease (i.e. disease-spec...

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Veröffentlicht in:BMC Genomics
Hauptverfasser: Ferrari, Raffaele, Kia, Demis A., Tomkins, James E., Hardy, John, Wood, Nicholas W., Lovering, Ruth C., Lewis, Patrick A., Manzoni, Claudia
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6000968/
https://ncbi.nlm.nih.gov/pubmed/29898659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-4804-9
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