A Rare Eicosanoid Precursor Analogue, Sciadonic Acid (5Z,11Z,14Z-20:3), Detected In Vivo in Hormone Positive Breast Cancer Tissue

Numerous genetic alterations of HSA 11q13 are found frequently in several cancer types, including breast cancer (BC). The 11q13 locus harbors FADS2 encoding Δ6 desaturation which is not functional in several cancer cell lines, including hormone positive MCF7 BC cells. In vitro, the non-functional FA...

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Veröffentlicht in:Prostaglandins Leukot Essent Fatty Acids
Hauptverfasser: Park, H. G., Zhang, J. Y., Foster, C., Sudilovsky, D., Schwed, D. A., Mecenas, J., Devapatla, S., Lawrence, P., Kothapalli, K. S. D., Brenna, J. T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5999340/
https://ncbi.nlm.nih.gov/pubmed/29886893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.plefa.2018.05.002
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