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The Role of Fatty Acid Desaturase (FADS) Genes in Oleic Acid Metabolism: FADS1 Δ7 desaturates 11-20:1 to 7,11-20:2

INTRODUCTION: In mammals, FADS2 catalyzes “front-end” Δ4-, Δ6-, and Δ8-desaturation of fatty acyl chains, whereas FADS1 has Δ5-desaturase activity. Eighteen and 20-carbon precursors to highly unsaturated n-3 and n-6 fatty acids are the usual substrates for FADS1 and FADS2. Our main objective was to...

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Bibliografske podrobnosti
izdano v:Prostaglandins Leukot Essent Fatty Acids
Main Authors: Park, Hui Gyu, Engel, Matthew G., Vogt-Lowell, Kyle, Lawrence, Peter, Kothapalli, Kumar S., Brenna, J. Thomas
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5806126/
https://ncbi.nlm.nih.gov/pubmed/29413358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.plefa.2017.11.004
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