Synergistic Role of Protein Phosphatase Inhibitor 1 and SERCA2a in the Acquisition of the Contractile Phenotype of Arterial Smooth Muscle Cells

BACKGROUND: Phenotypic modulation or switching of Vascular Smooth Muscle Cells (VSMC) from contractile/quiescent to a proliferative/synthetic phenotype plays a key role in vascular proliferative disorders, such as atherosclerosis and restenosis. Although several calcium handling proteins that contro...

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Udgivet i:Circulation
Main Authors: Lipskaia, Larissa, Bobe, Regis, Chen, Jiqiu, Turnbull, Irene C, Lopez, Jose J, Merlet, Elise, Jeong, Dongtaq, Karakikes, Ioannis, Ross, Alexandra S, Liang, Lifan, Mougenot, Nathalie, Atassi, Fabrice, Lompré, Anne-Marie, Tarzami, Sima T, Kovacic, Jason C, Kranias, Evangelia, Hajjar, Roger J, Hadri, Lahouaria
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5999331/
https://ncbi.nlm.nih.gov/pubmed/24249716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.113.002565
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