The exposure to uteroplacental insufficiency is associated with activation of unfolded protein response in postnatal life

Early life events are associated with the susceptibility to chronic diseases in adult life. Perturbations of endoplasmic reticulum (ER) homeostasis activate the unfolded protein response (UPR), which contributes to the development of metabolic alterations. Our aim was to evaluate liver UPR in an ani...

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Udgivet i:PLoS One
Main Authors: Deodati, Annalisa, Argemí, Josepmaría, Germani, Daniela, Puglianiello, Antonella, Alisi, Anna, De Stefanis, Cristiano, Ferrero, Roberto, Nobili, Valerio, Aragón, Tomás, Cianfarani, Stefano
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5999290/
https://ncbi.nlm.nih.gov/pubmed/29897997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198490
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