Uteroplacental insufficiency down regulates insulin receptor and affects expression of key enzymes of long-chain fatty acid (LCFA) metabolism in skeletal muscle at birth

BACKGROUND: Epidemiological studies have revealed a relationship between early growth restriction and the subsequent development of insulin resistance and type 2 diabetes. Ligation of the uterine arteries in rats mimics uteroplacental insufficiency and serves as a model of intrauterine growth restri...

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Detaylı Bibliyografya
Asıl Yazarlar: Germani, Daniela, Puglianiello, Antonella, Cianfarani, Stefano
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2008
Konular:
Original Investigation
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396605/
https://ncbi.nlm.nih.gov/pubmed/18485240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-7-14
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