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Expression and purification of the mammalian translocator protein for structural studies

The translocator protein (TSPO) is an 18 kDa polytopic membrane protein of the outer mitochondrial membrane, abundantly present in the steroid-synthesising cells. TSPO has been linked to a number of disorders, and it is recognised as a promising drug target with a range of potential medical applicat...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Graeber, Elisabeth, Korkhov, Volodymyr M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5999236/
https://ncbi.nlm.nih.gov/pubmed/29897975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198832
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