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Expression and purification of the mammalian translocator protein for structural studies

The translocator protein (TSPO) is an 18 kDa polytopic membrane protein of the outer mitochondrial membrane, abundantly present in the steroid-synthesising cells. TSPO has been linked to a number of disorders, and it is recognised as a promising drug target with a range of potential medical applicat...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Graeber, Elisabeth, Korkhov, Volodymyr M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5999236/
https://ncbi.nlm.nih.gov/pubmed/29897975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198832
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